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Crystal structure of the bromodomain of human BRPF1 in complex with a quinolinone ligand

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of the bromodomain of human BRPF1 in complex with a quinolinone ligand Descriptor: 1-METHYLQUINOLIN-2(1H)-ONE, NITRATE ION, Peregrin Authors: Tallant, C, Igoe, N, Bayle, E.D, Nunez-Alonso, G, Newman, J.A, Mathea, S, Savitsky, P, Fedorov, O, Brennan, P.E, Muller, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Fish, P, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2016-08-30 Release date: 2017-02-08 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. J. Med. Chem., 60, 2017
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2016-08-30
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