Genetic analysis data for a common-scale benchmark of ten blood-count-derived inflammatory indices: per-SNP instruments, outcome extractions, MR/LDSC result tables, and source GWAS summary statistics
收藏资源简介:
Restricted-access archive of the genetic-analysis inputs and outputs underlying the manuscript 'Markers, Not Makers' (submitted to Clinical Chemistry and Laboratory Medicine). Contents: (1) instruments_and_results.zip - per-SNP Mendelian randomization instrument tables (Blood Cell Consortium counts NEUT/LYMPH/MONO/PLT/WBC, BMI, and disease exposures for reverse MR), PLINK clumping outputs, outcome-side extractions at instrument SNPs (the harmonized exposure-outcome pairs are the rsid join of inst_*.pkl and out_*.pkl, as performed by the companion code record, concept DOI 10.5281/zenodo.23940167), mediation step files, and MR/LDSC result tables; (2) the raw GWAS summary statistics as downloaded (BCX trait files; GWAS Catalog harmonised files for CAD, T2D, CKD, stroke, NAFLD; Yengo 2018 BMI). All summary statistics are from public sources; no individual-level data. Archived for the author's records; not for distribution.



