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Crystal structure of dimeric RXR-LBD complexed with partial agonist NEt-4IB and TIF2 co-activator

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Protein Data Bank Japan2024-10-02 更新2026-03-21 收录
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Crystal structure of dimeric RXR-LBD complexed with partial agonist NEt-4IB and TIF2 co-activator Descriptor: 6-[ethyl-[4-(2-methylpropoxy)-3-propan-2-yl-phenyl]amino]pyridine-3-carboxylic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha Authors: Imai, D, Numoto, N, Nakano, S, Kakuta, H, Ito, N. Deposit date: 2019-11-13 Release date: 2020-11-18 Last modified: 2024-10-02 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for the full and partial agonist activities of retinoid X receptor alpha ligands with an iso-butoxy and an isopropyl group Biochem.Biophys.Res.Commun., 734, 2024
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2019-11-13
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