LSD1-CoREST in complex with T18, short soaking
收藏Protein Data Bank Japan2025-08-20 更新2026-04-25 收录
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LSD1-CoREST in complex with T18, short soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-(3-benzamidophenyl)-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) Authors: Caroli, J, Mattevi, A. Deposit date: 2023-01-10 Release date: 2024-08-07 Last modified: 2025-08-20 Method: X-RAY DIFFRACTION (3.13 Å) Cite: Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. Nat Commun, 16, 2025
创建时间：
2023-01-10
