首页/数据集/Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq)

Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq)

NIAID Data Ecosystem2026-03-11 收录

p53转录调控

PRO-seq/GRO-seq技术

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE53964 数据链接链接失效反馈

官方服务：

资源简介：

GRO-seq of HCT116 cells treated with Nutlin to activate p53 HCT116 cells were treated with Nutlin or DMSO for 1 hour

应用场景：

创建时间：

2019-05-15

p53转录调控

iASPP-p53相互作用

Raw Western blot and luciferase assay data to support the experimental results presented in the publication by Chen et al 2019 entitled "iASPP mediates p53 selectivity through a modular mechanism fine

NIAID Data Ecosystem90

A large intergenic non-coding RNA induced by p53 mediates global gene repression in the p53 transcriptional response. Mus musculus

p53转录调控

非编码RNA功能

Recently, more than a thousand large intergenic non-coding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved in mammalian genomes and thus presumably function in diverse biol

NIAID Data Ecosystem50

Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq). Homo sapiens

p53转录调控

PRO-seq/GRO-seq技术

GRO-seq of HCT116 cells treated with Nutlin to activate p53 Overall design: HCT116 cells were treated with Nutlin or DMSO for 1 hour

NIAID Data Ecosystem40

Global genomic profiling of p53-regulated genes. Mus musculus

p53转录调控

DNA损伤响应

p53 is a critical tumor suppressor and works as a stress-induced transcription factor to induce target genes mediating apoptosis, cell cycle arrest and senescence or other responses. To gain new insig

NIAID Data Ecosystem70

Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq)

增强子转录调控

PRO-seq/GRO-seq技术

Enhancers provide critical information directing cell-type specific transcriptional programs, regulated by binding of signal-dependent transcription factors and their associated cofactors. Here we rep

NIAID Data Ecosystem50

Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq)

资源简介：

相关数据集