Old Drawback on Azlactone Formation Revealed by a Combination of Theoretical and Experimental Studies
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资源简介：
New insights into the formation of azlactone heterocycles bearing different substituents are hereby presented. The sum of both kinetic and thermodynamic factors contributes for the formation of 2-alkyl or 2-aryl substituted azlactones, while the cyclization of 2-alcoxy azlactones is less favored. These results are in perfect accordance with experimental observations obtained by infrared (IR) and electrospray ionization mass spectrometry (ESI(+)-MS) of the crude reaction mixture.
提供机构：
SciELO journals
创建时间：
2018-10-24
