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Identification of genes showing an age related expression in iNKT1, 2, and 17 cells of BALB/c thymus

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=02dac9c9222cf12e0a530a0094ba3301
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资源简介:
In this study we applied RNA high-throughput seqencing to compare the global gene expression of young adult and aged iNKT subset in thymus of BALB/c mice.We found that only a small number of genes exerted a profound and statistically significant up- or downregulation upon ageing whereas a plethora of minor changes in the gene expression pattern were evident. However, significant age-related differences in expression of a variety of genes such as Histone genes, Gzma, CD25 and others mightcorrelate with functional adaptations to the drastically altering thmyus micro-environment during aging.
提供机构:
Hannover Medical School
创建时间:
2022-02-20
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