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Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage

ChEBI2015-03-31 更新2026-07-21 收录

关节软骨退行性病变

基因敲除模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-60401 数据链接链接失效反馈

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Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage

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创建时间：

2015-03-31

代谢疾病机制

基因敲除模型

Type 2 diabetes is typified by insulin-resistance in adipose tissue, skeletal muscle, and liver, leading to chronic hyperglycemia. Additionally, obesity and type 2 diabetes are characterized by chroni

DataONE2020-06-24 更新70

GARP cKO platelets are well formed and GARP cKO mice display unaltered hematological parameters.

血细胞形态学

基因敲除模型

GARP cKO platelets are well formed and GARP cKO mice display unaltered hematological parameters.

NIAID Data Ecosystem50

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

神经细胞蛋白质组学

基因敲除模型

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

Figshare2025-04-01 更新40

Gene expression data from the skin of Cdsniep-/-adult mice. Mus musculus

疾病分子机制

基因敲除模型

Peeling Skin Disease (PSD; OMIM 270300) is an inflammatory ichthyosis due to homozygous loss-of-function mutations in Corneodesmosin (CDSN) and characterized by lifelong patchy peeling of the skin ass

NIAID Data Ecosystem60

Gene expression in the embryonic Lrrc10 knockout heart. Mus musculus

发育基因表达

基因敲除模型

LRRC10 is a heart-specific gene required for proper cardiac function. The effects of Lrrc10 deletion on gene expression in the embryonic mouse heart was investigated. Overall design: Pregnant heterozy

NIAID Data Ecosystem50

Pregnane X receptor knockout mice display aging-dependent wearing of articular cartilage

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