Metadata record for the manuscript: Potential of Ultra-High-Resolution Photon-Counting CT of Bone Metastases: Initial experiences in Breast Cancer Patients

Summary

This
metadata record provides details of the data supporting the claims of the
related manuscript: “Potential of Ultra-High-Resolution
Photon-Counting CT of Bone Metastases: Initial experiences in Breast Cancer
Patients”.

The
data consist of computed tomography images in pseudonymised DICOM files.

The
related study aimed to explore the potential of higher spatial resolution for
imaging of bone metastases via the use of photon-counting detector (PCD)
computed tomography (CT), which utilises a novel CT detector technology based
on smaller detector pixels capable of counting and discriminating the energy of
single photons, as opposed to conventional CT scanners, which use
energy-integrating detectors (EID).

Data
access

All
demonstrated CT images are available with this metadata record as pseudonymised
DICOM files. The acquisition and
reconstruction parameters are available (as metadata in each file) so any user
will be able to adapt the CT window. These DICOM
files underlie Figures 1 and 2, and Table 3. The filenames include the figures
to which they apply, and are as follows: Fig1aFig1c.dcm,
Fig1bFig1d_highbin.dcm, Fig1bFig1d_lowbin.dcm, Fig1e_lowbin.dcm, Fig1e_highbin.dcm,
Fig2a.dcm, Fig2b.dcm, Fig2f.dcm, Fig2g.dcm, Fig3a.dcm, Fig3b.dcm,
Fig3c_highbin.dcm, Fig3c_lowbin.dcm, Fig3d.dcm. Additionally, the Excel
spreadsheet npj_breast_cancer_PCCT_Reader-Study.xlsx contains the lesions
diameters according to the four readers. All readers are co-authors on the
related manuscript and allow the publication of their assessments.

All data on
the reader's opinion on different features in EID and PCD CT images are
presented in Table 1 of the related manuscript. The patient
and tumour characteristics at the time of initial diagnosis, which are
contained in Table 2 of the related manuscript, are data from given physicians’
letters, and so cannot be shared without jeopardising patients’ anonymity. Any
requests for access to this data should be made to the corresponding author, E.
Wehrse ([e-mail]).

Name
of Institutional Review Board or ethics committee that approved the study

This prospective case
series was approved both by the Ethics Committee of the Medical Faculty of
Heidelberg according to the Declaration of Helsinki of 2013 and the Federal
Office for Radiation Protection and all patients gave their informed consent
(German Clinical Trials Register DRKS00017759).