Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 19.
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Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 19. Descriptor: 5-phenylthieno[2,3-d]pyrimidin-4(3H)-one, 6-amino-5-{[(3S)-4,4-difluoro-1-{[4-(trifluoromethoxy)phenyl]acetyl}pyrrolidin-3-yl]oxy}-N-methylpyridine-3-carboxamide, High affinity nerve growth factor receptor Authors: Greasley, S.E, Johnson, E, Kraus, M.L, Cronin, C.N. Deposit date: 2018-05-29 Release date: 2018-07-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. J. Med. Chem., 61, 2018
创建时间：
2018-05-29
