Fig-8-Pgingivalis.tif
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Figure 8. Schematic illustration. P. gingivalis infection polarizes macrophages toward the M1 phenotype via activating the IL-6/STAT3 pathway. The M1 macrophages accelerate apical inflammation and bone destruction via secretion of IL-6, TNF-α, and RANKL, which are pro-inflammatory mediators that can impede osteogenesis and promote osteoclastogenesis
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SciELO Data
创建时间:
2022-11-03



