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Synthesis and SAR of guanine based analogues for HPPK inhibitors

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Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Synthesis and SAR of guanine based analogues for HPPK inhibitors Descriptor: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7-(2-HYDROXYETHYL)-8-MERCAPTOGUANINE Authors: Chhabra, S, Peat, T.S, Swarbrick, J. Deposit date: 2011-12-22 Release date: 2013-01-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Exploring the Chemical Space Around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme Hppk. Plos One, 8, 2013
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2011-12-22
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