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Human esophageal dysplasia (16 cases) vs. esophageal squamous cell carcinoma (59 cases)

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE46452
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资源简介:
Our aim is to identify frequent genomic aberrations both in ESCC and esophageal dysplasia, and to discover important copy number-driving genes and microRNAs in ESCC. We carried out array-based comparative genomic hybridization (array CGH) on 59 ESCC resection samples and 16 dysplasia biopsy samples. Expression of genes at 11q13.3 was analyzed by real-time PCR and immunohistochemistry (IHC). Integrated analysis was performed to identify genes or microRNAs with copy number-expression correlations. Two group experiment, esophageal dysplasia vs. esophageal squamous cell carcinoma. Biological replicates: 16 dysplasias vs. 59 carcinomas
创建时间:
2015-10-12
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