Five- and Six-Coordinated Silver(I) Complexes Derived from 2,6-(Pyridyl)iminodiadamantanes: Sustained Release of Bioactive Silver toward Bacterial Eradication

Silver­(I)
complexes of two designed tridentate ligands, namely, 2,6-(pyridyl)­iminoditriazaadamantane
(pydTAm) and 2,6-(pyridyl)­iminodiadamantane (pydAm), have been synthesized
and structurally characterized. [Ag­(pydTAm)2]­(CF3SO3) (1), the hitherto unknown mer isomer of a silver­(I) octahedral complex, crystallizes in a highly
symmetric body-centered cubic I4̅3m space group. Quite in contrast, the AgI center in the
analogous [Ag­(pydAm)2]­(CF3SO3) (2) complex resides in a trigonal-bipyramidal geometry and
crystallizes in a triclinic P1̅ space group
with two crystallographically independent molecules in the asymmetric
unit. Complex 1 exhibits exceptional solubility in aqueous
media and leads to the efficient eradication of several bacterial
strains upon sustained release of bioactive silver.