Investigation of the changes induce by inhibiting mitochondrial respiration on DNA methylation and hydroxymethylation in periosteal cells. Investigation of the changes induce by inhibiting mitochondrial respiration on DNA methylation and hydroxymethylation in periosteal cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA814240
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资源简介：
The metabolic changes induced by blocking mitochondrial respiration result in a decrease of 5hmC levels. This experiment aims to further investigate the changes in DNA demethylation induced by Antimycin A treatment using both regular bisulfite- and oxidative bisulfite-chip sequencing. Overall design: Periosteal cells isolated from 3 pools of mice were treated either by Antimycin A (AMA) or vehicle as control. 10 days after isolation, the effect on DNA methylation and hydroxymethylation was investigated.
创建时间：
2022-03-09
