Genome-wide maps of chromatin state in Ad-UBE3B and control lymphoma cells
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https://www.ncbi.nlm.nih.gov/sra/SRP242564
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资源简介:
We report the application of single-molecule-based sequencing technology for high-throughput profiling of RNAPII with promoters in mammalian cells. We performed ChIP sequencing with antibody to total RNAPII in UBE3B overexpression and control group. Inspection of multiple individual traces and global analyses showed that UBE3B overexpression globally reduced association of RNAPII with promoters. Overall design: We performed ChIP sequencing with antibody to total RNAPII in UBE3B overexpression and control group and globally analysed association of RNAPII with promoters.
创建时间:
2020-12-23



