Lung transcriptome sequencing anlysis in Male Sprague-Dawley rats

we dissected the chemical components of MXSG by liquid chromatography-mass spectrometry (LC-ESI-MS/MS) and analyzed the intervention pathways of MXSG based on components detected through network pharmacology. At the same time, the therapeutic effect of MXSG on COVID-19 was explained through published articles, and the relevant regulatory mechanism was proposed. Then, in this study, the regulatory effect of MXSG on inflammatory lung injury was explorated through transcriptome results.本研究通过液相色谱-电喷雾电离-串联质谱（LC-ESI-MS/MS）剖析了MXSG的化学成分，并基于网络药理学方法对其检测得到的活性成分的干预通路进行分析。同时，本研究依托已发表文献阐明了MXSG对新型冠状病毒肺炎（COVID-19）的治疗作用，并提出了相关调控机制。最后，本研究通过转录组（transcriptome）测序结果，探究了MXSG对炎症性肺损伤的调控作用。