Dual_guide_CRISPR_Cas9_library_to_identify_novel_synthetic_lethal_gene_pairs
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
The aim of the study is to identify novel synthetically lethal gene pairs within cancer cells that could potentially be therapeutically targeted in the future. To achieve this, we designed a bespoke dual guide CRISPR library targeting our gene pairs of interest and used this library to screen a panel of cell lines from a background of melanoma, NSCLC and pancreatic cancer.
创建时间：
2023-04-01
