1H MR Spectroscopy and Diffusion MRI data reveal recovery of metabolic and microstructural alterations in the brain of chronic mild stress exposed rats

The data comprises longitudinal 1H MR Spectroscopy (1H MRS) data from ventral hippocampus and in-vivo diffusion MRI (d-MRI) data of the brain from control and chronic mild stress (CMS) induced anhedonic rats. In-vivo 1H MRS and d-MRI data were acquired using a 9.4 T preclinical imaging system. Data was acquired at the age of week 18 (Week 1 post-CMS exposure), week 20 (Week 3 post-CMS exposure) and week 25 (Week 8 post-CMS exposure) in the anhedonic group and at the age of week 18 and week 22 in the control group. Diffusion MRI and 1H MRS data of anhedonic rat brain are in two different ".rar" files name as "Raw_d-MRI_In-vivo" and "Raw_data_MRS". Control data at week 18 named as Ctr1_"animal number" and at the age of week 22 named as Ctr2_"animal number". Data from the anhedonic group named after a three-digit arbitrary number, a week number post-CMS exposure and again a one or two digits arbitrary number. For example, 106W1_29 is an anhedonic rat at week 1 post-CMS exposure.

本数据集包含来自对照及慢性轻度应激（CMS）诱导快感缺乏的大鼠腹侧海马区的纵向1H磁共振波谱（1H MRS）数据，以及大脑的体内扩散磁共振成像（d-MRI）数据。体内1H MRS和d-MRI数据采用9.4 T的前临床成像系统采集。数据采集时间分别为CMS暴露后第1周（18周龄）、第3周（20周龄）及第8周（25周龄）的快感缺乏组，以及对照组的18周龄和22周龄。快感缺乏大鼠大脑的扩散MRI和1H MRS数据分别存储于两个不同的“rar”文件中，分别命名为“Raw_d-MRI_In-vivo”和“Raw_data_MRS”。对照数据在18周龄时命名为Ctr1_“动物编号”，在22周龄时命名为Ctr2_“动物编号”。快感缺乏组的数据以三位任意数字、CMS暴露后的周数以及再次出现的单个或双位数任意数字命名。例如，106W1_29代表CMS暴露后第1周的快感缺乏大鼠。