Collagen type I binds integrin alpha11beta1

The integrin alpha11beta1 along with alpha1beta1, alpha2beta1 and alpha10beta1 are referred to as a collagen receptor subgroup of the integrin family. Integrin alpha11beta1 binds preferentially to the fibril-forming collagen types I and II, binding to type III is weaker and collagens IV and VI are poor ligands (Zhang et al. 2003).

整合素α11β1，连同α1β1、α2β1及α10β1，被统称为整合素家族中的胶原蛋白受体亚组。整合素α11β1优先与形成纤维的胶原蛋白类型I和II结合，与类型III的结合较弱，而胶原蛋白IV和VI则作为较差的配体（张等，2003年）。