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RNA-seq of a VHL-/- human renal cancer cell line 786-0 transfected with 3 vectors. RNA-seq of a VHL-/- human renal cancer cell line 786-0 transfected with 3 vectors

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NIAID Data Ecosystem2026-03-13 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJEB48871
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The human renal cancer cell line 786-0 was transfected with 3 vectors allowing the doxycycline-inducible expression of 1) the full length wild type sequence of VHL: 786-0 VHL WT, VHL+/+, 2) the R167Q mutant : 786-0 R167Q, VHL mutated, 3) the empty vector : 786-0 EV, VHL-/-. The aim of the study was to examine whether the VHL-R167Q mutation, which is associated with a high risk of developping clear cell renal carcinomas, could impact the plasticity of renal carcinoma cells.
创建时间:
2021-12-10
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