Characterization of E13.5 forelimb gene expression after Hic1 knockout
收藏Alliance of Genome Resources2026-08-01 收录
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To investigate the effect of the mesenchymal quiescence regulator, Hic1, on forelimb development, we collected forelimbs from conventional Hic1 knockout animals to animals with a limb specific Hic1 knockout driven by the proposed limb mesenchyme specific Prrx1-Cre line. We then homogenized the forelimbs for RNAseq analysis and normalized by FPKM. Comparative gene expression profiling analysis of RNA-seq data from animals using two knockout strategies to delete Hic1.
