Genomic occupancy of the INO80 complex [II]. Genomic occupancy of the INO80 complex [II]

We mapped 4 subunits of the INO80 complex using ChIP-seq in HepG2 liver cancer cells. We found a subclass of sites occupied by the INO80 ATPase subunit, but not by any accessory subunits that we call 'Non-canonical' INO80 sites. These sites are characterized by repressed chromatin. Overall design: ChIP-seq was performed for INO80 subunits in HepG2 cells and was processed for ChIP as previously described (Raab et al 2015), followed by high throughput sequencing. Reanalysis of GSE97411 Samples.