Functional study of CTNNA1 in HEK293T cells
收藏科学数据银行2025-06-11 更新2026-04-23 收录
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资源简介：
We provide comprehensive proteomic profiling of CTNNA1 and its ubiquitylated forms in HEK293T cells, including: (1) Interactome analysis of native and ubiquitylated CTNNA1 via immunoaffinity purification-mass spectrometry (IP-MS); (2) Ubiquitylation site mapping using LC-MS/MS. Dataset includes raw spectra, and processed identification files.Raw data were analyzed using MaxQuant (version 1.6.17.0 and version 2.0.3.0) searched against human FASTA database, or mouse CTNNA1 FASTA (P26231) for CTNNA1 ubiquitylation sites identification. For ubiquitylation sites identification, the (GlyGly) remnants search was enabled.
提供机构：
Ruona Shi; Laboratory of Proteomics and Ubiquitin Signaling, Center for Cell Lineage Altas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; University of Chinese Academy of Sciences, Beijing 100049, China; Xiaoxiao Tang; Xiaofei Zhang; Wenfeng Wu
创建时间：
2025-06-11
