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Biop-C: A Method for Chromatin Interactome Analysis of Solid Cancer Needle Biopsy Samples

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP305720
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Our results demonstrate the utility of our Biop-C method in investigating the 3D genome organization in solid cancers, and the importance of 3D genome organization in regulating oncogenes in nasopharyngeal cancer. Overall design: We have analysed 3 nasopharyngeal cancer biopsy samples using our novel Biop-C method as well as 2 replicates of NPC cell line HK1 using arima Hi-C kit protocol. To test the reproducibility of the method, we performed Biop-C on 2 replicates of a biopsy samples. For comparision with healthy tissue, we performed hic on near normal epithelial cell line NP-69. >>>Raw data not provided for human biopsy samples due to patient privacy concerns<<<
创建时间:
2021-09-23
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