Dynamics of m6A RNA methylome during leukemogenesis reveals a role of PRMT6-MFSD2A signaling axis in maintaining AML stem cells.[RIP-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218610
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We delineate a comprehensive m6A landscape during acute myeloid leukemia (AML) development, and identify PRMT6, regulated by IGF2BP2, acting as a key for leukemia stem cell maintenance by restraining MFSD2A expression and docosahexaenoic acid level. m6A readers (IGF2BP2, YTHDF2, YTHDC1) RIP-seq of primary murine LICs
创建时间：
2023-12-05
