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Alternative splicing in human metabolic liver disease

NIAID Data Ecosystem2026-05-01 收录

RNA选择性剪接

代谢性肝病

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP471777 数据链接链接失效反馈

官方服务：

资源简介：

We analyzed alternative splicing of RNA in liver samples from subjects with NAFLD or NASH, or subjects with no history of liver disease.

应用场景：

创建时间：

2024-01-05

RNA选择性剪接

病毒-宿主相互作用

Background Alternative splicing (AS) is a central mechanism of genetic regulation which modifies the sequence of RNA transcripts in higher eukaryotes. AS has been shown to increase both the variabili

NIAID Data Ecosystem50

Treatment of a metabolic liver disease by in vivo prime editing in mice

基因编辑治疗

代谢性肝病

Prime editing is a highly versatile CRISPR-based genome editing technology with the potential to correct the vast majority of genetic defects1. However, correction of a disease phenotype in vivo in so

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Additional file 8: of Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells

基因调控

RNA选择性剪接

ZFP36_vs_Ctrl_IR_RAS_p0.05_known. (TXT 4 kb)

Figshare2024-02-13 更新20

Additional file 9 of OBSCN undergoes extensive alternative splicing during human cardiac and skeletal muscle development

RNA选择性剪接

肌肉发育调控

Additional file 9: Table S8. Spearman (rank) correlation of expression of splicing factors with exon inclusion levels PSI values across the skeletal muscle samples.

Figshare2025-03-02 更新40

SPOP Regulates the Expression Profiles and Alternative Splicing Events in Human Hepatocytes

基因表达调控

RNA选择性剪接

SPOP Regulates the Expression Profiles and Alternative Splicing Events in Human Hepatocytes

NIAID Data Ecosystem20