Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor
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Crystal structure of human protein arginine methyltransferase PRMT6 bound to SAH and an aryl pyrazole inhibitor Descriptor: GLYCEROL, N-{[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methyl}-N-methylethane-1,2-diamine, Protein arginine N-methyltransferase 6, ... Authors: Swinger, K.K, Boriack-Sjodin, P.A. Deposit date: 2015-02-09 Release date: 2015-04-22 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound. Acs Med.Chem.Lett., 6, 2015
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2015-02-09
