Source Data Extended Data Figure 5

This file contains the source data for Extended Data Figure 5a-f.
a,b, Boxplots (a) and heatmaps (b) showing ChIP-seq signal changes of H3K27me3 and H3K27ac at different types of 4C regions (gained, lost and unchanged 4C loops) in EV and DKO cells. The same 4C regions are connected by gray lines in the boxplot. c,d, Boxplots (c) and heatmaps (d) of ChIP-seq signal changes of H3K27me3 and H3K27ac at different types of 4C regions (gained, lost and unchanged 4C loops) in S1KO and DKO cells. The same 4C regions are connected by gray lines in the boxplot. e,f, Boxplots (e) and heatmaps (f) showing ChIP-seq signal changes of H3K27me3 and H3K27ac at different types of 4C regions (gained, lost and unchanged 4C loops) in EV and S1KO cells. The same 4C regions are connected by gray lines in the boxplot. Box and whisker plot: whiskers were extended to the furthest value that is no more than 1.5 times the inter-quartile range. The boxes represent the 25th percentile, median, and 75th percentile. The boxes represent the 25th percentile, median, and 75th percentile (a,c,e); n = 2 biologically independent replicates (a-f); two-sided Wilcoxon Signed-Rank paired test (a,c,e).