Population Architecture using Genomics and Epidemiology (PAGE): Causal Variants Across the Life Course (CALiCo): Hispanic Community Health Study / Study of Latinos (HCHS/SOL)

This sub-study [phs000555](study.cgi?study_id=phs000555) PAGE CALiCo SOL contains genotype data and selected phenotype of subjects available from the [phs000555](study.cgi?study_id=phs000555). Summary level phenotypes for the NHLBI HCHS SOL Cohort study participants can be viewed at the top-level study page [phs000810](study.cgi?study_id=phs000810) HCHS SOL Cohort. Individual level phenotype data and molecular data for all HCHS SOL Cohort top-level study and sub-study are available by requesting Authorized Access to the NHLBI HCHS SOL Cohort [phs000810](study.cgi?study_id=phs000810) study.

**PAGE CALiCo SOL**<br>

The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a multi-center epidemiologic study in Hispanic/Latino populations to determine the role of acculturation in the prevalence and development of disease, and to identify risk factors playing a protective or harmful role in Hispanics/Latinos. The study is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) and six other institutes, centers, and offices of the National Institutes of Health (NIH).

The population of 16,000 persons of Hispanic/Latino origin, specifically Cuban, Puerto Rican, Mexican, and Central/South American, was recruited through four Field Centers affiliated with San Diego State University, Northwestern University in Chicago, Albert Einstein College of Medicine in the Bronx area of New York, and the University of Miami. Seven additional academic centers serve as scientific and logistical support centers.

Study participants aged 18-74 years completed an extensive clinic exam and assessments to determine baseline risk factors. Annual follow-up interviews are conducted to determine health outcomes of interest. Study results are disseminated through scientific journals and also conveyed to the communities involved in the study in order to improve public health at the local level.

This study is part of the Population Architecture using Genomics and Epidemiology (PAGE) study ([phs000356](study.cgi?study_id=phs000356)).