Severe gestational diabetes mellitus in lean dams sex-specifically affects the growth and inflammatory status of the juvenile mice offspring

We investigated how maternal gestational diabetes (GDM) impacts the metabolic status of offspring. GDM was induced in CD1 mice consuming a fast-food diet (FFD) by repeated low-dose streptozotocin injections before mating. Offspring of normoglycemic standard chow or the FFD consuming dams served as controls. In 4-week-old offspring weaned to standard chow, plasma concentrations of extracellular DNA, inflammatory markers, and those characterizing cardiometabolic status (glycemia, liver lipid content; body, organ, and fats weight) were determined. The dataset contains all previously mentioned parameters and variables.