Inhibition of HeLa cell toxicity by attenuated Y. pestis in the presence of selected small molecule inhibitors.

The HeLa cells were incubated with attenuated Y. pestis KIM19 strain in the presence of small molecules in DMEM medium supplemented with 10% FBS as described under Materials and Methods. Cell toxicity was scored by calculating the percentage of rounded versus the squamous cells under a microscope. Only data for molecules showing 10% or more inhibition of cell rounding at 50 µM inhibitor concentration are shown.