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RNA polymerases deal with obstacles during transcription elongation that need to be removed
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Realtime Kinetics of in-vitro RNA Polymerase Transcription
smFRET realtime kinetics experiments of RNAP transitioning from initiation to elongation. Measurements were performed both on a 8-spot smFRET system and a single-spot usALEX-smFRET system. <
DataCite Commons2020-09-03 更新90
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T)
SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) Descriptor: DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit b
Protein Data Bank Japan2024-06-19 更新10
Altering the sigma D factor of RNA polymerase and thereby improving the robustness of microbial cell factories.
We propose a robustness optimization strategy that combined gene mining and global transcription regulation. As a proof of concept, the common industrial host Escherichia coli was engineered as an exa
NIAID Data Ecosystem10
Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin
Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C
Protein Data Bank Japan2023-08-30 更新30
RNA polymerase I structure with an alternative dimer hinge
RNA polymerase I structure with an alternative dimer hinge Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit
Protein Data Bank Japan2024-11-20 更新10
