Replication results for top signals from APCAT (Stage1 N = 18,604) in additional studies (Stage 2 N = 15,576) and in GABRIEL.

aPositions/alleles are relative to the forward strand of NCBI build36. b,cResults from GABRIEL are from a re-analysis using fixed-effects meta-analysis, excluding the B58C and ECRHS2 cohorts which are included in Stage2 or with occupational asthma (see Methods), and are for the APCAT SNP or the best available proxy. All p values are two-tailed.