Crystal structure of c-Met-M1250T in complex with SAR125844.
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Crystal structure of c-Met-M1250T in complex with SAR125844. Descriptor: 1-(6-{[6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}-1,3-benzothiazol-2-yl)-3-[2-(morpholin-4-yl)ethyl]urea, Hepatocyte growth factor receptor Authors: Vallee, F, Houtmann, J, Marquette, J.-P. Deposit date: 2016-01-19 Release date: 2016-11-23 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844). J.Med.Chem., 59, 2016
创建时间：
2016-01-19
