Figure S1 - C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut Granules

Alignment of C. elegans (Ce) BLOC-1 subunits to (Dm) D. melanogaster and (Hs) human homologues. The sequences under the lines denote highly conserved motifs identified by Cheli & Dell’Angelica (2010). The following sequences were used for (A) BLOS1: human NP_001478, D. melanogaster NP_725401, C. elegans NP_499262; (B) BLOS2: human NP_776170, D. melanogaster NP_648427, C. elegans NP_500967; (C) BLOS4: human NP_060836, D. melanogaster NP_648414, C. elegans NP_495247; (D) Dysbindin: human NP_115498, D. melanogaster NP_649064, C. elegans NP_492628; (E) Muted: human NP_958437, D. melanogaster NP_001036744, C. elegans NP_501119. (PDF)