MPTP-mouse model constitutes a well-known model of neuroinflammation and mitochondrial failure occurring in Parkinson’s disease (PD). Although it has been extensively reported that nitric oxide (NO●)

NIAID Data Ecosystem70

Supplementary Material for: Pharmacological Characterization of a Highly Selective and Potent Partial Agonist of the MT 2 Melatonin Receptor

褪黑激素

昼夜节律睡眠障碍

Background/Aims: The MT2 melatonin receptor is a potential target for treating circadian rhythm sleep disorders. This study aims to characterize the recently identified MT2 melatonin receptor agonist.

NIAID Data Ecosystem50

Low serum melatonin levels are associated with erectile dysfunction

褪黑激素

勃起功能障碍

ABSTRACT Objective: Melatonin is a hormone secreted from the pineal gland and has anti-oxidative and anti-inflammatory effects. Oxidative stress is considered as an important factor in the etiology of

DataCite Commons2020-08-28 更新90

Melatonin Regulates Microglia-derived Exosomes to Reduce Postoperative Delirium

褪黑激素

术后谵妄

At the animal level, a rat model of postoperative delirium was constructed by deep anesthesia and treated intraperitoneally and respectively with low, medium, and high doses of melatonin. The behavior

DataCite Commons2023-04-22 更新60