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A Simple, Short, and Flexible Synthesis of Viridiofungin Derivatives

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/A_Simple_Short_and_Flexible_Synthesis_of_Viridiofungin_Derivatives/3066751
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Described herein is a simple, flexible, and efficient synthesis of the skeleton of the viridiofungins, a family of microbial secondary metabolites. The synthesis utilizes an asymmetric aldol reaction of a chiral oxazolidinone, a diastereoselective alkylation of a chiral 1,3-dioxolan-2-one, and a geometrically selective alkene cross-metathesis reaction as the key C−C bond-forming steps.
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2016-03-01
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