A Study on Molecular Interactions and Antimycotic Properties of Thiadiazole/Coumarin Derivatives with Selected Polyene and Azole Antibiotics Showing Synergistic or Antagonistic Effects

The data was generated during the Miniatura 8 project, registration number: 2024/08/X/NZ1/01460.This collection includes data obtained in the above research task and serves as the basis for the creation of scientific publications, which will present new synergistic systems with available antifungal drugs and provide a preliminary description of their mechanism of action.The collection contains data on: the structures of the tested compounds, antifungal activity data obtained using the broth microdilution method from 48 hours of measurements (bioscreen), FICI calculation results, data obtained using UV-Vis spectroscopy, fluorescence spectroscopy, fluorescence lifetime spectroscopy using the TCSPC (Time-Correlated Single Photon Counting) method, NMR spectroscopy, and cytotoxicity tests.