Characterization of the CORVET complexes of Tetrahymena thermophila
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.omicsdi.org/dataset/pride/PXD014895
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资源简介:
In endolysosomal networks, two hetero-hexameric tethers called HOPS and CORVET are found widely throughout eukaryotes. The ciliate Tetrahymena thermophila is a unicellular organism with elaborate endolysosomal pathways. Curiously, Tetrahymena and related protozoa have lost HOPS. Tetrahymena encodes multiple paralogs of most CORVET subunits, assembled into six distinct hexameric complexes, including a distinct Vps8 subunit. Here we analyze the composition of these complexes immunoisolated by affinity capture using the Vps8-FLAG paralogs as bait.
创建时间:
2019-12-19



