Scnn1g

ENCODES a protein that exhibits ligand-gated sodium channel activity; sodium ion transmembrane transporter activity; WW domain binding; INVOLVED IN intracellular sodium ion homeostasis; response to hypoxia; sodium ion import across plasma membrane; PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal recessive pseudohypoaldosteronism type 1 (ortholog); bronchiectasis 3 (ortholog); FOUND IN apical plasma membrane; cell surface; sodium channel complex; INTERACTS WITH 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3-isobutyl-1-methyl-7H-xanthine; 6-propyl-2-thiouracil

编码一种表现出配体门控钠通道活性、钠离子跨膜转运活性、WW结构域结合的蛋白质；参与细胞内钠离子稳态的维持、对缺氧的反应、钠离子跨质膜转运；参与阿米洛利药理学途径、苯氟噻嗪药理学途径、布美他尼药理学途径；与自闭症谱系障碍（同源物）相关；与常染色体隐性假性醛固酮减少症1型（同源物）、支气管扩张症3（同源物）相关；位于顶端质膜、细胞表面、钠通道复合物；与3'-氨基-3'-脱氧-N(6),N(6)-二甲基腺苷、3-异丁基-1-甲基-7H-黄嘌呤、6-丙基-2-硫尿嘧啶相互作用。