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TH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis

ChEBI2013-05-22 更新2026-07-21 收录

神经母细胞瘤模型

癌症转移机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42548 数据链接链接失效反馈

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资源简介：

TH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis

应用场景：

创建时间：

2013-05-22

癌症转移机制

转录组学分析

We tested if the changes in cell invasion and migration observed after MCM7 depletion manifested in an altered gene expression profile. For this purpose, we performed RNAseq analysis after MCM7 knock-

NIAID Data Ecosystem40

Flag-RBM47 HITS-CLIP in brain metastatic derivatives of MDA-MB-231

RNA结合蛋白靶标

癌症转移机制

Brain metastatic breast cancer cells were subjected to HITS-CLIP to identify the targets of the RNA binding protein RBM47 MDA231-BrM2a is characterized in PMID: 19421193; Related data published toget

NIAID Data Ecosystem40

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

NFIC1 suppresses migration and invasion of breast cancer cells through interferon-mediated Jak-STAT pathway

癌症转移机制

Jak-STAT信号通路

NFIC1, the longest isoform of NFIC, is essential for the regulation on spatiotemporal expressions of drug-metabolizing genes in liver. However, the role of NFIC1 in breast cancer is not clear. Here we

NIAID Data Ecosystem40

Additional file 2 of An integrated multi-omics approach to identify regulatory mechanisms in cancer metastatic processes

癌症转移机制

多组学整合分析

Additional file 2. Gene set characterization. Gene set characterization of the DE genes between early and late stages. The downregulated genes are significantly enriched for cancer-related gene signat

NIAID Data Ecosystem30

TH-MYCN Mice with Caspase-8 Deficiency Develop Advanced Neuroblastoma with Bone Marrow Metastasis

资源简介：

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