X-ray crystal structure of wild type HIV-1 protease in complex with GRL-142
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5tys
下载链接
链接失效反馈官方服务：
资源简介：
X-ray crystal structure of wild type HIV-1 protease in complex with GRL-142 Descriptor: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, Protease Authors: Yedidi, R.S, Hayashi, H, Aoki, M, Das, D, Ghosh, A.K, Mitsuya, H. Deposit date: 2016-11-21 Release date: 2017-10-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.007 Å) Cite: A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency. Elife, 6, 2017
创建时间：
2016-11-21
