GDP-bound KRAS G12C in complex with YK-8S
收藏Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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GDP-bound KRAS G12C in complex with YK-8S Descriptor: (2~{S})-1-[4-[7-(8-ethynyl-7-fluoranyl-naphthalen-1-yl)-8-fluoranyl-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]-2-oxidanyl-propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Zhang, Z.M, Wang, R.L. Deposit date: 2023-05-20 Release date: 2024-01-31 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.60037058083 Å) Cite: Simultaneous Covalent Modification of K-Ras(G12D) and K-Ras(G12C) with Tunable Oxirane Electrophiles. J.Am.Chem.Soc., 145, 2023
创建时间：
2023-05-20
