Figure S1 in File S1 - Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data

Asthma-associated SNPs and H3K4me1 (enhancer) enriched regions in the human IKZF3 locus of different cell/tissue types. From top to bottom, using the UCSC genome browser, are displayed: the gene track (genes), all the SNPs not associated with asthma, the SNPs associated with asthma (red are GWAS-identified SNPs, blue are SNPs in linkage disequilibrium), H3K4me1 ChIP-seq track (green) for different cell/tissue types (named on the left) underlined by the corresponding peak-calling track (black boxes). For the blood CD4+ T cells, peak calling tracks from seven samples/cell-types are displayed. The red box shows an H3K4me1 peak that is present only in CD4+ T cells. (PDF)