Enhancer profiling in Esrrb-/- ES cells [4C-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP226497
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We uncover a pivotal role for ESRRB in demarcating ESC-specific enhancer units, and propose that ESRRB's developmentally-regulated extinction precipitates their decommissioning with impact on the rewiring of the pluripotency transcriptional programme upon embryo implantation. Overall design: Profiling chromatin interactions at Klf4 enhancer locus with 4C-seq.
创建时间:
2020-03-10



