Gene Sets Analysis Results for Selected Gene Ontology (GO) Terms.

The final list of 29 most highly significant adipose genes was analyzed using Gene Profiler to detect enrichment of genes in various biological functional categories. A global set of all genes was used as the control group. P values are shown for several relevant GO categories containing ADH1A and ADH1B. Several categories contained only these two genes. The genes were analyzed as an ordered list based on FDR values and numbers of shared traits. Only manually curated data was used for the analysis to avoid potentially spurious results. Significance for these GO terms was increased approximately 10-fold when analysis was restricted to the two genes ADH1A and ADH1B. Essentially identical results were obtained using the WebGestalt analytical engine. All significance values were corrected for multiple testing.
Gene Sets Analysis Results for Selected Gene Ontology (GO) Terms.