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Effect of CuCl2 on transcriptional expression profile of A549 cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214566
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To investigate the effects of disrupting Cu homeostasis on A549 cells in vitro, we treated cells with sDMEM supplemented with 0µM(control), 30µM, or 200µM CuCl2 for 2 or 4 hours Following RNA extraction, poly(A) enrichment library generation, and sequencing, we then performed differential expression analysis of extracted RNA, comparing 30µM or 200µM-CuCl2-treated cells to 0µM-CuCl2-treated cells at 2 hours and 4 hours
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2024-09-11
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