Sus scrofa Targeted Locus (Loci). Sus scrofa

The interplay between host genetics, gut microbiota and host physiological responses has a crucial importance for animal health and performance. In swine, genetic markers for gut homeostasis have been identified, however, scarce data on their effect on the gut microbial composition and the host metabolic and immune response in healthy pigs are available. This study investigated the effect of Single Nucleotide Polymorphisms (SNPs) located on candidate gene for gut homeostasis on the mid-jejunal microbiota composition, expression of genes related to inflammation and glycomic binding pattern profile, and on blood serum targeted metabolomics profile and performance parameters of growing healthy pigs.