human protein farnesyltransferase complexed with FPP and R115777
收藏Protein Data Bank Japan2023-08-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1sa4
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human protein farnesyltransferase complexed with FPP and R115777 Descriptor: 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... Authors: Reid, T.S, Beese, L.S. Deposit date: 2004-02-06 Release date: 2004-06-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Biochemistry, 43, 2004
创建时间：
2004-02-06
